Searchable abstracts of presentations at key conferences in endocrinology

ea0035p409 | Diabetes complications | ECE2014

Associated study of polymorphic variants in the gene for superoxide dysmutase (Mn SOD) and different types of diabetes mellitus

Pashkunova Sylvia , Ivanov Valentin , Savov Alexey

Superoxid dysmutase (SOD) is a key antioxidant enzyme engaged in detoxication of superoxide radicals. Ala/Val substitution in Mn SOD leads to a change in the effectiveness of the action of the enzyme. This polymorphism we analyzed among several groups patients with diabetes and we compared with control group of healthy volunteers. It is proved an association connection of tracked marker in some of the groups of patients with diabetes compared to the rest population sample. Suc...